Congenital Absence of Pain.

was then grossly distended and similarly filled by organising thrombus. The only other abnormalities were: (i) A small infarct in the upper lobe of the right lung. (2) Fatty. change in the liver. (3) Slight enlargement of the mesenteric lymph glands. Histology. Renal, ulnar and mesenteric arteriesnormal. Coronary arteries: The aneurysms were filled by organizing thbombus extensively infiltrated with polymorpho-nuclear leucocytes. The wall of the affected areas of the coronary arteries was grossly thickened, the outstanding lesion being splitting of the internal elastic lamina and extensive proliferation of fibroblasts spreading through the remains of the media and adventitia into the peri-adventitial tissue.. The whole lesion was widely infiltrated by polymorpho-nuclear leucocytes and eosinophils and, to a lesser extent, plasma cells. (Fig. 2).